This Article Full Text Free Full Text (PDF) Free Submit a response Alert me when this article is cited Alert me when eLetters are posted Alert me if a correction is posted Citation Map Services Email this article to a friend Similar articles in this journal Alert me to new issues of the journal Add to My Personal Article Archive Download to citation manager Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Google Scholar Articles by Eggleston, P. A. Search for Related Content PubMed Articles by Eggleston, P. A.

The Environment and Asthma in US Inner Cities^*

^* From Johns Hopkins University, School of Medicine, Department of Pediatrics, Baltimore, MD.

Correspondence to: Peyton A. Eggleston, MD, The Johns Hopkins University, Department of Pediatrics, School of Medicine/CMCSC 1102, Baltimore, MD 21287-3923; e-mail: pegglest{at}jhmi.edu

Poor, minority children living in US inner cities have increased rates of asthma morbidity and mortality. Factors that contribute to these increased rates are varied and complex, with current evidence suggesting that the environment is an important causative factor. Respiratory morbidity is often the result of allergens and air pollutants. Additionally, for children living in urban environments, underlying societal susceptibility factors specific to the inner city serve to increase asthma morbidity. Even though ambient pollutants have been declining in US cities, asthma morbidity and mortality rates have been increasing. Indoor pollutants are closely linked to increased asthma prevalence and morbidity. While the understanding of environmental influences is still relatively limited, we can say that indoor exposures are more important than ambient pollutants, and we know that bioaerosols containing allergenic proteins are especially important. Additionally, certain particulate aerosols and ozone cause inflammation individually and may act synergistically to enhance the acute and chronic IgE-mediated inflammation. The purpose of this article is to review the data relating exposure to environmental pollutants and airborne allergens, and the relationship of this exposure to asthma prevalence and morbidity in order to inform plans for public health programs to reduce an asthma burden.

Key Words: asthma • environment • inner cities

This article has been cited by other articles:

				C. M. Clancy, J. P. Kiley, and K. B. Weiss Eliminating Asthma Disparities Through Multistakeholder Partnerships Chest, November 1, 2007; 132(5): 1422 - 1424. [Full Text] [PDF]