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Right arrow Methodologic Quality of Studies Evaluating Atrial Fibrillation/Flutter after Cardiac Surgery
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(Chest. 2005;128:17S-23S.)
© 2005 American College of Chest Physicians

Methodological Approach*

American College of Chest Physicians Guidelines for the Prevention and Management of Postoperative Atrial Fibrillation After Cardiac Surgery

Lee A. Fleisher, MD; Eric B. Bass, MD, MPH and Peter McKeown, MD, FCCP

* From the Department of Anesthesia (Dr. Fleisher), University of Pennsylvania Health System, Philadelphia, PA; Johns Hopkins University School of Medicine (Dr. Bass), Baltimore, MD; and Asheville Veterans Affairs Medical Center (Dr. McKeown), Asheville, NC.

Correspondence to: Lee A. Fleisher, MD, University of Pennsylvania Health System, 3400 Spruce Street, Philadelphia, PA 19104; e-mail: Fleishel{at}uphs.upenn.edu

Atrial fibrillation remains a common and challenging problem following cardiac surgery. The American College of Chest Physicians, through the Health and Science Policy Committee, established a panel to develop a set of clinical practice guidelines for the management or prophylaxis of atrial fibrillation or flutter in patients undergoing coronary artery bypass surgery. The panel based its guidelines on a systematic review of the literature that included a computerized search of PubMed and CENTRAL, the Cochrane Collaboration database, as well as a search of selected journals and references in key articles. Studies were eligible for review if they were controlled trials. Paired reviewers assessed the quality of each eligible study and extracted relevant data. The resulting data were assembled into evidence tables organized by key management questions. The panel derived recommendations that were based on this review of evidence and were formulated according to the ACCP protocol for grading evidence and strength of recommendations.

Key Words: atrial fibrillation • evidence-based medicine • guidelines • methodology • systematic review







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